Giuseppe is the High Priest of the Fygul Cestemus cult, who is found out to be responsible for spreading the Malfested scourge in the land. He is fought and defeated by the player and Estes, sending a Golem to fight them after his defeat. He appears to be interested in Estes' power to heal malfestation.
He later reveals that he, along with the Fygul Cestemus created Estes with alchemy to be a template for the creation of other warriors. The High Priest is later killed by the player in one of his attempts to take Estes.